Bioavailability of Nutrients from Animal-Derived Foods Versus Other Sources of Foods: A Comprehensive Literature Review

Modern nutritional science places increasing emphasis not only on absolute nutrient content, but primarily on bioavailability and interactions with the food matrix. This paper presents a comprehensive comparison of the bioavailability of protein, vitamins (A, D, and B 12 ), and key minerals (iron, zinc, and calcium) from animal-source foods (ASF) and plant-based alternatives.

Bioavailability of Nutrients from Animal-Derived Foods Versus Other Sources of Foods: A Comprehensive Literature Review.
Asia Food Times editorial cover generated for this article. Source: Nutrients / Europe PMC. Licence: CC BY.

Modern nutritional science places increasing emphasis not only on absolute nutrient content, but primarily on bioavailability and interactions with the food matrix. This paper presents a comprehensive comparison of the bioavailability of protein, vitamins (A, D, and B 12 ), and key minerals (iron, zinc, and calcium) from animal-source foods (ASF) and plant-based alternatives.

What the research examined

Based on the literature indexed in the Web of Science, Scopus, PubMed, and ScienceDirect databases, this review assessed nutrient absorption and matrix effects, including both antinutritional factors and health-promoting compounds. The analysis shows that while ASF generally exhibit higher baseline bioavailability of several essential micronutrients and protein (measured by PDCAAS and DIAAS) due to the absence of phytates and oxalates, plant-based matrices offer distinct physiological benefits, including dietary fiber and phytonutrients.

What the findings mean

Moreover, the lower bioavailability in plant sources can be significantly improved through food processing techniques (e.g., fermentation, germination, thermal treatment) and strategic dietary combinations. Therefore, adequate nutrient intake depends not only on the food's origin but also on its preparation methods and the overall dietary pattern. It is also important that the best diet is both nutritionally adequate and sustainable for the individual and the environment.

Study authors: Rudy M.. This report is based on the openly licensed abstract and source record and has been formatted for newsroom reading.

Original source

Nutrients

https://europepmc.org/articles/PMC13567421

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